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  • 14:03, 27 March 2025 Lawrence talk contribs created page Vanguard trials (Created page with "= Vanguard Trials = A '''vanguard trial'''—also referred to as a pilot trial embedded within a larger trial, i.e., '''internal pilot'''—is a type of feasibility study conducted as the initial phase of a definitive randomized controlled trial (RCT). Its purpose is to test the feasibility of the main trial’s methods before fully launching it. Unlike standalone pilot trials, the data collected in a vanguard trial can be incorporated into the main trial if predefined...")